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查看说明书Recombinant Human BRAF Protein
Cat#:TP01364应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-BRAF (Thr401) Recombinant Rabbit mAb |
| Cat No.: | RMA03089 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ICC/IF, IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr401 of human B Raf |
| Calculated Molecular Weight: | 84 kDa |
| Observed Molecular Weight: | 84 kDa |
| GenBank Accession Number: | P15056 |
| Gene ID (NCBI): | 673 |
| Synonyms: | NS7; B-raf; BRAF1; RAFB1; B-RAF1 |
| Background: | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
| Category: | Primary Ab |
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