Recombinant Human BMP Receptor II/BMPR2/PPH1 Protein(C-Fc-6His)
Cat#:TP04694应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Recombinant Human BMPR2 Protein (His Tag) |
Cat No.: | TP06595 |
TargetID: | Q13873 |
Source: | HEK293 Cells |
Gene Accession Number: | 659 |
Peptide Sequence: | Ser27-Ile151 |
Tag: | C-His |
Purity: | >90% as determined by SDS-PAGE. |
Formulation: | Freeze-dried powder |
Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
Category: | Protein |
Species Reactivity: | Human |
Predicted Molecular Mass: | 25kDa |
Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
Background: | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. |
Size: | 10ug 50ug 100ug 200ug 1mg |
Synonyms: | BMPR-II;BMPR3;BMR2;BRK-3;POVD1;PPH1;T-ALK |