蛋白
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检测试剂盒
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分子生物学
规格：
查看说明书Recombinant Human BMP Receptor II/BMPR2/PPH1 Protein(C-Fc-6His)
Cat#:TP04694应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Human BMPR2 / BMPR-II Protein (His & Fc tag) |
| Cat No.: | TP08454 |
| TargetID: | Q13873 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 659 |
| Peptide Sequence: | Met 1-Ile 151 |
| Tag: | C-His & Fc |
| Purity: | >95% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 42 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | BMPR-II;BMPR3;BMR2;BRK-3;POVD1;PPH1;T-ALK |
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