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CD27 Rabbit pAb

Cat No.: DPA01838
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Product Name: CD27 Rabbit pAb
Cat No.: DPA01838
Clonality: Polyclonal
Species Reactivity: Human, Rat
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human CD27
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 49 kDa
GenBank Accession Number: P26842
Gene ID (NCBI): 939
Synonyms: T14; S152; Tp55; TNFRSF7; S152. LPFS2
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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