Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7)
Cat#:TP01497应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CD27 Rabbit pAb |
Cat No.: | DPA03923 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:50-1:200 FC: 1:20-1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human CD27 |
Calculated Molecular Weight: | 29 kDa |
Observed Molecular Weight: | 49 kDa |
GenBank Accession Number: | P26842 |
Gene ID (NCBI): | 939 |
Synonyms: | T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
Background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |