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规格：
查看说明书Recombinant Human Insulin Protein
Cat#:TP07505应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Insulin Rabbit pAb |
| Cat No.: | DPA01980 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | IHC |
| Recommended Dilution: | IHC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Insulin |
| Calculated Molecular Weight: | 12 kDa |
| GenBank Accession Number: | P01308 |
| Gene ID (NCBI): | 3630 |
| Synonyms: | IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10 |
| Background: | This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020] |
| Category: | Primary Ab |
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