Recombinant Human Insulin Protein
Cat#:TP07505应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Insulin Rabbit pAb |
Cat No.: | DPA04609 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Insulin |
Calculated Molecular Weight: | 12 kDa |
Observed Molecular Weight: | 12 kDa |
GenBank Accession Number: | P01308 |
Gene ID (NCBI): | 3630 |
Synonyms: | IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10 |
Background: | After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] |
Category: | Primary Ab |