Recombinant Human IDO1 Protein
Cat#:TP02561应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Indoleamine 2,3-dioxygenase Rabbit pAb |
Cat No.: | DPA03068 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,ICC/IF |
Recommended Dilution: | WB: 1:2000 ICC/IF: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Indoleamine 2,3-dioxygenase |
Calculated Molecular Weight: | 45 kDa |
Observed Molecular Weight: | 45 kDa |
GenBank Accession Number: | P14902 |
Gene ID (NCBI): | 3620 |
Synonyms: | IDO; INDO; IDO-1 |
Background: | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
Category: | Primary Ab |