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查看说明书Recombinant Human IDO1 Protein
Cat#:TP02561应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Indoleamine 2,3-dioxygenase Rabbit pAb |
| Cat No.: | DPA04140 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Indoleamine 2,3-dioxygenase |
| Calculated Molecular Weight: | 45 kDa |
| Observed Molecular Weight: | 45 kDa |
| GenBank Accession Number: | P14902 |
| Gene ID (NCBI): | 3620 |
| Synonyms: | IDO; INDO; IDO-1 |
| Background: | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
| Category: | Primary Ab |
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