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GCLC Rabbit pAb

Cat No.: DPA03887
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Product Name: GCLC Rabbit pAb
Cat No.: DPA03887
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human GCLC
Calculated Molecular Weight: 73 kDa
Observed Molecular Weight: 73 kDa
GenBank Accession Number: P48506
Gene ID (NCBI): 2729
Synonyms: GCL; GCS; GLCL; GLCLC
Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
Category: Primary Ab
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