蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书GCLC Rabbit pAb
Cat#:DPA02625应用：WB,IP
| Product Name: | GCLC Rabbit pAb |
| Cat No.: | DPA03990 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000-1:5000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GCLC |
| Calculated Molecular Weight: | 73 kDa |
| Observed Molecular Weight: | 73 kDa |
| GenBank Accession Number: | P48506 |
| Gene ID (NCBI): | 2729 |
| Synonyms: | GCL; GCS; GLCL; GLCLC |
| Background: | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010] |
| Category: | Primary Ab |
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