Recombinant Human NRAS Protein
Cat#:TP03193应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Ras Rabbit pAb |
Cat No.: | DPA04328 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,IP |
Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 IP: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Ras |
Calculated Molecular Weight: | 22 kDa |
Observed Molecular Weight: | 22 kDa |
GenBank Accession Number: | P01111 |
Gene ID (NCBI): | 4893 |
Synonyms: | NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1 |
Background: | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |
Category: | Primary Ab |