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Ras Rabbit pAb

Cat No.: DPA04328
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Product Name: Ras Rabbit pAb
Cat No.: DPA04328
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,IP
Recommended Dilution: WB: 1:1000-1:5000
ICC/IF: 1:20-1:50
IP: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Ras
Calculated Molecular Weight: 22 kDa
Observed Molecular Weight: 22 kDa
GenBank Accession Number: P01111
Gene ID (NCBI): 4893
Synonyms: NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
Category: Primary Ab
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